MicroRNA-27a Promotes Proliferation, Migration and Invasion by Targeting MAP2K4 in Human Osteosarcoma Cells

Background: Osteosarcoma is a high-grade malignant bone neoplasm. Although the introduction of chemotherapy has reduced its mortality, more than 50% of patients develop chemoresistance and have an extremely poor prognosis due to pulmonary metastasis. Several molecular pathways contributing to osteos...

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Bibliographic Details
Main Authors: Weibo Pan, Haibao Wang, Ruan Jianwei, Zhaoming Ye
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:http://www.karger.com/Article/FullText/356679