Reduction of resistance artery stiffness by treatment with the AT1-receptor antagonist losartan in essential hypertension
In spontaneously hypertensive rats resistance artery structure, endothelial dysfunction and geometry-independent wall stiffness were reduced by an angiotensin AT 1 -receptor antagonist. In previous studies of human hypertension, interruption of the renin-angiotensin system corrected small artery str...
Main Authors: | Jeong Bae Park, Hope D Intengan, Ernesto L Schiffrin |
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Format: | Article |
Language: | English |
Published: |
Hindawi - SAGE Publishing
2000-03-01
|
Series: | Journal of the Renin-Angiotensin-Aldosterone System |
Online Access: | https://doi.org/10.3317/jraas.2000.009 |
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