Reduction of resistance artery stiffness by treatment with the AT1-receptor antagonist losartan in essential hypertension

In spontaneously hypertensive rats resistance artery structure, endothelial dysfunction and geometry-independent wall stiffness were reduced by an angiotensin AT 1 -receptor antagonist. In previous studies of human hypertension, interruption of the renin-angiotensin system corrected small artery str...

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Bibliographic Details
Main Authors: Jeong Bae Park, Hope D Intengan, Ernesto L Schiffrin
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2000-03-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2000.009