<i>BRAF</i> Mutation in Colorectal Cancers: From Prognostic Marker to Targetable Mutation

The Raf murine sarcoma viral oncogene homolog B (<i>BRAF</i>) mutation is detected in 8–12% of metastatic colorectal cancers (mCRCs) and is strongly correlated with poor prognosis. The recent success of the BEACON CRC study and the development of targeted therapy have led to the determin...

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Bibliographic Details
Main Authors: Izuma Nakayama, Toru Hirota, Eiji Shinozaki
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/11/3236