<i>BRAF</i> Mutation in Colorectal Cancers: From Prognostic Marker to Targetable Mutation
The Raf murine sarcoma viral oncogene homolog B (<i>BRAF</i>) mutation is detected in 8–12% of metastatic colorectal cancers (mCRCs) and is strongly correlated with poor prognosis. The recent success of the BEACON CRC study and the development of targeted therapy have led to the determin...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-11-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/12/11/3236 |