Exploring Valine Metabolism in Astrocytic and Liver Cells: Lesson from Clinical Observation in TBI Patients for Nutritional Intervention

The utilization of alternative energy substrates to glucose could be beneficial in traumatic brain injury (TBI). Recent clinical data obtained in TBI patients reported valine, β-hydroxyisobutyrate (ibHB) and 2-ketoisovaleric acid (2-KIV) as three of the main predictors of TBI outcome. In particular,...

Full description

Bibliographic Details
Main Authors: Sarah Sonnay, Nicolas Christinat, Jonathan Thevenet, Andreas Wiederkehr, Anirikh Chakrabarti, Mojgan Masoodi
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/8/11/487