Alkaloid-rich fraction of Himatanthus lancifolius contains anti-tumor agents against leukemic cells

Alkaloid-rich fraction of Himatanthus lancifolius contains anti-tumor agents against leukemic cells

The effects of the alkaloid-rich fraction of Himatanthus lancifolius (Müll. Arg) Woodson on normal marrow cells and leukemic cell lines were investigated. After 48 h exposure, the proliferation assay showed significant cell growth inhibition for Daudi (0.1-10 µg/mL), K-562 (1-10 µg/mL), and REH cell...

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Bibliographic Details
Main Authors: Melissa Pires de Lima, Luciana Farhat Hilst, Fernanda Vanessa Rechinbach Mattana, Cid Aimbiré de Moraes Santos, Almeriane Maria Weffort-Santos
Format: Article
Language:English
Published: Universidade de São Paulo 2010-06-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Apocynaceae
Proliferação celular
Himatanthus lancifolius
Alcalóides indólicos
Leucemia
Extrato vegetal
Cell proliferation
Indole alkaloids
Leukemia
Plant extract
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000200014

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000200014

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