Pioglitazone Induces Cardiomyocyte Apoptosis and Inhibits Cardiomyocyte Hypertrophy Via VEGFR-2 Signaling Pathway

Pioglitazone Induces Cardiomyocyte Apoptosis and Inhibits Cardiomyocyte Hypertrophy Via VEGFR-2 Signaling Pathway

Abstract Background: Pioglitazone has been widely used as an insulin-sensitizing agent for improving glycemic control in patients with type 2 diabetes mellitus. However, cardiovascular risk and protective effects of pioglitazone remain controversial. Objectives: In this study, we investigated whet...

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Bibliographic Details
Main Authors: Wenliang Zhong, Wen Jin, Shanghua Xu, Yanqing Wu, Shunxiang Luo, Minlie Liang, Lianglong Chen
Format: Article
Language:English
Published: Sociedade Brasileira de Cardiologia (SBC) 2018-07-01
Series:Arquivos Brasileiros de Cardiologia
Subjects:
Apoptose
Miócitos Cardíaco
Cardiomegalia
Insuficiência Cardíaca/fisiopatologia
Anti-Hipertensivos
Tiazolidinedionas
Resistência à Insulina
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2018001400162&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2018001400162&lng=en&tlng=en

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