Ferritin overexpression in Drosophila glia leads to iron deposition in the optic lobes and late-onset behavioral defects

Ferritin overexpression in Drosophila glia leads to iron deposition in the optic lobes and late-onset behavioral defects

Cellular and organismal iron storage depends on the function of the ferritin protein complex in insects and mammals alike. In the central nervous system of insects, the distribution and relevance of ferritin remain unclear, though ferritin has been implicated in Drosophila models of Alzheimers'...

Full description

Bibliographic Details
Main Authors: Stylianos Kosmidis, Jose A. Botella, Konstantinos Mandilaras, Stephan Schneuwly, Efthimios M.C. Skoulakis, Tracey A. Rouault, Fanis Missirlis
Format: Article
Language:English
Published: Elsevier 2011-07-01
Series:Neurobiology of Disease
Subjects:
Optic lamina
Inclusions
Metals
Circadian clock
Restless legs
Hyperferritinemia
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111000957

Internet

http://www.sciencedirect.com/science/article/pii/S0969996111000957

Similar Items