Gut microbiota in experimental murine model of Graves’ orbitopathy established in different environments may modulate clinical presentation of disease

Gut microbiota in experimental murine model of Graves’ orbitopathy established in different environments may modulate clinical presentation of disease

Abstract Background Variation in induced models of autoimmunity has been attributed to the housing environment and its effect on the gut microbiota. In Graves’ disease (GD), autoantibodies to the thyrotropin receptor (TSHR) cause autoimmune hyperthyroidism. Many GD patients develop Graves’ orbitopat...

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Bibliographic Details
Main Authors: Giulia Masetti, Sajad Moshkelgosha, Hedda-Luise Köhling, Danila Covelli, Jasvinder Paul Banga, Utta Berchner-Pfannschmidt, Mareike Horstmann, Salvador Diaz-Cano, Gina-Eva Goertz, Sue Plummer, Anja Eckstein, Marian Ludgate, Filippo Biscarini, Julian Roberto Marchesi, the INDIGO consortium
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Microbiome
Subjects:
Graves’ orbitopathy
Graves’ disease
Induced animal model
Gut microbiota
TSHR
Metataxonomics
Online Access:http://link.springer.com/article/10.1186/s40168-018-0478-4

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http://link.springer.com/article/10.1186/s40168-018-0478-4

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