Early Segmental White Matter Fascicle Microstructural Damage Predicts the Corresponding Cognitive Domain Impairment in Cerebral Small Vessel Disease Patients by Automated Fiber Quantification

Early Segmental White Matter Fascicle Microstructural Damage Predicts the Corresponding Cognitive Domain Impairment in Cerebral Small Vessel Disease Patients by Automated Fiber Quantification

Objective: To characterize earlier damage pattern of white matter (WM) microstructure in cerebral small vessel disease (CSVD) and its relationship with cognitive domain dysfunction.Methods: A total of 144 CSVD patients and 100 healthy controls who underwent neuropsychological measurements and diffus...

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Bibliographic Details
Main Authors: Lili Huang, Xin Chen, Wenshan Sun, Haifeng Chen, Qing Ye, Dan Yang, Mengchun Li, Caimei Luo, Junyi Ma, Pengfei Shao, Hengheng Xu, Bing Zhang, Xiaolei Zhu, Yun Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
automated fiber quantification
cerebral small vessel disease
cognitive decline
damage mode
white matter microstructure damage
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2020.598242/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2020.598242/full

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