Dehydrodiisoeugenol inhibits colorectal cancer growth by endoplasmic reticulum stress-induced autophagic pathways

Dehydrodiisoeugenol inhibits colorectal cancer growth by endoplasmic reticulum stress-induced autophagic pathways

Abstract Background Dehydrodiisoeugenol (DEH), a novel lignan component extracted from nutmeg, which is the seed of Myristica fragrans Houtt, displays noticeable anti-inflammatory and anti-allergic effects in digestive system diseases. However, the mechanism of its anticancer activity in gastrointes...

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Bibliographic Details
Main Authors: Changhong Li, Kui Zhang, Guangzhao Pan, Haoyan Ji, Chongyang Li, Xiaowen Wang, Xin Hu, Ruochen Liu, Longfei Deng, Yi Wang, Liqun Yang, Hongjuan Cui
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Colorectal cancer
Dehydrodiisoeugenol (DEH)
Autophagy inhibition
Endoplasmic reticulum (ER) stress
Anticancer agent
Online Access:https://doi.org/10.1186/s13046-021-01915-9

Internet

https://doi.org/10.1186/s13046-021-01915-9

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