EZH2-Mediated microRNA-375 Upregulation Promotes Progression of Breast Cancer via the Inhibition of FOXO1 and the p53 Signaling Pathway

Breast cancer (BC) is the most common gynecologic tumor worldwide where aberrant expression of microRNAs (miRNAs) is frequently involved. Here, we evaluated the function of miR-375 on BC development and the molecules implicated. Differentially expressed genes between tumor and paired normal tissues...

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Bibliographic Details
Main Authors: Xin Guan, Aiping Shi, Yabin Zou, Meiyang Sun, Yue Zhan, Yi Dong, Zhimin Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Genetics
Subjects:
p53
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.633756/full