Attenuation of toll-like receptor expression and function in latent tuberculosis by coexistent filarial infection with restoration following antifilarial chemotherapy.

Attenuation of toll-like receptor expression and function in latent tuberculosis by coexistent filarial infection with restoration following antifilarial chemotherapy.

Mycobacterium tuberculosis (Mtb) and filarial coinfection is highly prevalent, and the presence of filarial infections may regulate the Toll-like receptor (TLR)-dependent immune response needed to control Mtb infection. By analyzing the baseline and mycobacterial antigen-stimulated expression of TLR...

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Bibliographic Details
Main Authors: Subash Babu, Sajid Q Bhat, N Pavan Kumar, R Anuradha, Paul Kumaran, P G Gopi, C Kolappan, V Kumaraswami, Thomas B Nutman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2710006?pdf=render

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http://europepmc.org/articles/PMC2710006?pdf=render

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