The Capsule Depolymerase Dpo48 Rescues Galleria mellonella and Mice From Acinetobacter baumannii Systemic Infections

The Capsule Depolymerase Dpo48 Rescues Galleria mellonella and Mice From Acinetobacter baumannii Systemic Infections

The emergence of multidrug- and extensively drug-resistant Acinetobacter baumannii has made it difficult to treat and control infections caused by this bacterium. Thus, alternatives to conventional antibiotics for management of severe A. baumannii infections is urgently needed. In our previous study...

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Bibliographic Details
Main Authors: Yannan Liu, Sharon Shui Yee Leung, Yatao Guo, Lili Zhao, Ning Jiang, Liyuan Mi, Puyuan Li, Can Wang, Yanhong Qin, Zhiqiang Mi, Changqing Bai, Zhancheng Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Microbiology
Subjects:
Acinetobacter baumannii
capsule depolymerase
Galleria mellonella model
mouse model
systemic infection
antivirulence
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00545/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.00545/full

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