PKCθ regulates T cell motility via ezrin-radixin-moesin localization to the uropod.

Cell motility is a fundamental process crucial for function in many cell types, including T cells. T cell motility is critical for T cell-mediated immune responses, including initiation, activation, and effector function. While many extracellular receptors and cytoskeletal regulators have been shown...

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Bibliographic Details
Main Authors: Judy L Cannon, Francois Asperti-Boursin, Kenneth A Letendre, Ivy K Brown, Katy E Korzekwa, Kelly M Blaine, Sreenivasa R Oruganti, Anne I Sperling, Melanie E Moses
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3826749?pdf=render