LONP1 and ClpP cooperatively regulate mitochondrial proteostasis for cancer cell survival
Abstract Mitochondrial proteases are key components in mitochondrial stress responses that maintain proteostasis and mitochondrial integrity in harsh environmental conditions, which leads to the acquisition of aggressive phenotypes, including chemoresistance and metastasis. However, the molecular me...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2021-02-01
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| Series: | Oncogenesis |
| Online Access: | https://doi.org/10.1038/s41389-021-00306-1 |