miR-196b-mediated translation regulation of mouse insulin2 via the 5'UTR.

The 5' and the 3' untranslated regions (UTR) of the insulin genes are very well conserved across species. Although microRNAs (miRNAs) are known to regulate insulin secretion process, direct regulation of insulin biosynthesis by miRNA has not been reported. Here, we show that mouse microRNA...

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Bibliographic Details
Main Authors: Amaresh C Panda, Itishri Sahu, Shardul D Kulkarni, Jennifer L Martindale, Kotb Abdelmohsen, Arya Vindu, Jomon Joseph, Myriam Gorospe, Vasudevan Seshadri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4086887?pdf=render