Increased expression of interleukin (IL)-6 family members and receptors in urinary bladder with cyclophosphamide (CYP)-induced bladder inflammation in female rats

Increased expression of interleukin (IL)-6 family members and receptors in urinary bladder with cyclophosphamide (CYP)-induced bladder inflammation in female rats

Recent studies suggest that JAK-STAT signaling pathways contribute to increased voiding frequency and referred pain of CYP-induced cystitis in rats. Potential upstream chemical mediator(s) that may be activated by CYP-induced cystitis to stimulate JAK/STAT signaling are not known in detail. In the...

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Bibliographic Details
Main Authors: Beatrice eGirard, Bopaiah P Cheppudira, Susan eMalley, Kristin eSchutz, Victor eMay, Margaret A Vizzard
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-02-01
Series:Frontiers in Neuroscience
Subjects:
Urothelium
gp130
detrusor smooth muscle
LIF
Q-PCR
western blotting
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2011.00020/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2011.00020/full

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