Neuroinflammation is induced by tongue-instilled ZnO nanoparticles via the Ca2+-dependent NF-κB and MAPK pathways

Neuroinflammation is induced by tongue-instilled ZnO nanoparticles via the Ca2+-dependent NF-κB and MAPK pathways

Abstract Background The extensive biological applications of zinc oxide nanoparticles (ZnO NPs) in stomatology have created serious concerns about their biotoxicity. In our previous study, ZnO NPs were confirmed to transfer to the central nervous system (CNS) via the taste nerve pathway and cause ne...

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Bibliographic Details
Main Authors: Huimin Liang, Aijie Chen, Xuan Lai, Jia Liu, Junrong Wu, Yiyuan Kang, Xinying Wang, Longquan Shao
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Particle and Fibre Toxicology
Subjects:
Zinc oxide nanoparticles
Taste nerve
Neuroinflammation
Calcium ion
Online Access:http://link.springer.com/article/10.1186/s12989-018-0274-0

Internet

http://link.springer.com/article/10.1186/s12989-018-0274-0

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