Increased betulinic acid induced cytotoxicity and radiosensitivity in glioma cells under hypoxic conditions

Increased betulinic acid induced cytotoxicity and radiosensitivity in glioma cells under hypoxic conditions

<p>Abstract</p> <p>Background</p> <p>Betulinic acid (BA) is a novel antineoplastic agent under evaluation for tumor therapy. Because of the selective cytotoxic effects of BA in tumor cells (including gliomas), the combination of this agent with conservative therapies (s...

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Bibliographic Details
Main Authors: Paschke Reinhard, Kappler Matthias, Wichmann Henri, Keßler Jacqueline, Passin Sarina, Zschornak Martin P, Bache Matthias, Kaluđerović Goran N, Kommera Harish, Taubert Helge, Vordermark Dirk
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Radiation Oncology
Subjects:
betulinc acid
glioma cells
hypoxia
irradiation
Online Access:http://www.ro-journal.com/content/6/1/111

Internet

http://www.ro-journal.com/content/6/1/111

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