Probing the Structure of DNA Aptamers with a Classic Heterocycle.

DNA aptamers are synthetic, single-stranded DNA oligonucleotides selectedby SELEX methods for their binding with specific ligands. Here we present ethidiumbinding results for three related DNA aptamers (PDB code: 1OLD, 1DB6, and 2ARG)that bind L-argininamide (L-Arm). The ligand bound form of each ap...

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Bibliographic Details
Main Authors: G. Reid Bishop, Arthur E. Wood IV
Format: Article
Language:English
Published: MDPI AG 2004-02-01
Series:Molecules
Subjects:
DNA
Online Access:http://www.mdpi.com/1420-3049/9/3/67/