Modulation of the colon cancer cell phenotype by pro-inflammatory macrophages: A preclinical model of surgery-associated inflammation and tumor recurrence.

Peritoneal infection after colorectal cancer surgery is associated with a higher rate of tumor relapse. We have recently proposed that soluble inflammatory factors released in response to a postoperative infection enhance tumor progression features in residual tumor cells. In an effort to set up mod...

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Bibliographic Details
Main Authors: María Marcuello, Xavier Mayol, Eloísa Felipe-Fumero, Jaume Costa, Laia López-Hierro, Silvia Salvans, Sandra Alonso, Marta Pascual, Luís Grande, Miguel Pera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5819803?pdf=render