Defining the Roles of IFN-γ and IL-17A in Inflammation and Protection against Helicobacter pylori Infection.

CD4+ T cells have been shown to be essential for vaccine-induced protection against Helicobacter pylori infection. However, the effector mechanisms leading to reductions in the gastric bacterial loads of vaccinated mice remain unclear. We have investigated the function of IFN-γ and IL-17A for vaccin...

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Bibliographic Details
Main Authors: Louise Sjökvist Ottsjö, Carl-Fredrik Flach, Staffan Nilsson, Rene de Waal Malefyt, Anna K Walduck, Sukanya Raghavan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4500503?pdf=render