Investigating molecular crowding within nuclear pores using polarization-PALM

Investigating molecular crowding within nuclear pores using polarization-PALM

The key component of the nuclear pore complex (NPC) controlling permeability, selectivity, and the speed of nucleocytoplasmic transport is an assembly of natively unfolded polypeptides, which contain phenylalanine-glycine (FG) binding sites for nuclear transport receptors. The architecture and dynam...

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Bibliographic Details
Main Authors: Guo Fu, Li-Chun Tu, Anton Zilman, Siegfried M Musser
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-09-01
Series:eLife
Subjects:
nuclear pores
super-resolution microscopy
PALM
polarization PALM
rotational diffusion
Online Access:https://elifesciences.org/articles/28716

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