Investigating molecular crowding within nuclear pores using polarization-PALM
The key component of the nuclear pore complex (NPC) controlling permeability, selectivity, and the speed of nucleocytoplasmic transport is an assembly of natively unfolded polypeptides, which contain phenylalanine-glycine (FG) binding sites for nuclear transport receptors. The architecture and dynam...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-09-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/28716 |