Reductive amination with zinc powder in aqueous media

Zinc powder in aqueous alkaline media was employed to perform reductive amination of aldehydes with primary amines. The corresponding secondary amines were obtained in good yields along with minor amounts of hydrodimerization byproducts. The protocol is a green alternative to the use of complex hydr...

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Bibliographic Details
Main Authors: Giovanni B. Giovenzana, Daniela Imperio, Andrea Penoni, Giovanni Palmisano
Format: Article
Language:English
Published: Beilstein-Institut 2011-08-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.7.125