Vagaries of fluorochrome reporter gene expression in Foxp3+ regulatory T cells.

CD4(+)CD25(+) regulatory T (Treg) cell lineage commitment and expression of the transcription factor Foxp3 can be induced at the CD4(+)CD8(+) double-positive (DP) and CD4(+)CD8(?) single-positive stages of thymic development, as well as in postthymic CD4(+) T cells in peripheral lymphoid tissues. Th...

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Bibliographic Details
Main Authors: Sonja Schallenberg, Cathleen Petzold, Pei-Yun Tsai, Tim Sparwasser, Karsten Kretschmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3412838?pdf=render