Cooling induces phase separation in membranes derived from isolated CNS myelin.

Purified myelin membranes (PMMs) are the starting material for biochemical analyses such as the isolation of detergent-insoluble glycosphingolipid-rich domains (DIGs), which are believed to be representatives of functional lipid rafts. The normal DIGs isolation protocol involves the extraction of li...

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Bibliographic Details
Main Authors: Julio M Pusterla, Emanuel Schneck, Sérgio S Funari, Bruno Demé, Motomu Tanaka, Rafael G Oliveira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5600379?pdf=render