miRNA expression profiling in migrating glioblastoma cells: regulation of cell migration and invasion by miR-23b via targeting of Pyk2.

Glioblastoma (GB) is the most common and lethal type of primary brain tumor. Clinical outcome remains poor and is essentially palliative due to the highly invasive nature of the disease. A more thorough understanding of the molecular mechanisms that drive glioma invasion is required to limit dispers...

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Bibliographic Details
Main Authors: Joseph C Loftus, Julianna T D Ross, Kimberly M Paquette, Vincent M Paulino, Sara Nasser, Zhongbo Yang, Jean Kloss, Seungchan Kim, Michael E Berens, Nhan L Tran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3382150?pdf=render