Probing the role of PPARγ in the regulation of late-onset Alzheimer's disease-associated genes.

Peroxisome proliferator-activated receptor-γ (PPARγ), is a transcription factor that governs pathways, such as lipid metabolism and immune response, that have been implicated in the etiology of LOAD. Previously, we established HepG2-derived cell-lines with stable knockdown of PPARγ gene, and showed...

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Bibliographic Details
Main Authors: Julio Barrera, Shobana Subramanian, Ornit Chiba-Falek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5933777?pdf=render