In vivo monitoring of the recruitment and activation of AP-1 by Arf1

Abstract AP-1 is a clathrin adaptor recruited to the trans-Golgi Network where it can interact with specific signals found in the cytosolic tail of cargo proteins to incorporate them into clathrin-coated vesicles for trafficking. The small G protein Arf1 regulates the spatiotemporal recruitment of A...

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Bibliographic Details
Main Authors: Etienne Sauvageau, Peter J. McCormick, Stephane Lefrancois
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07493-1