Association of pre-chemotherapy peripheral blood pro-inflammatory and coagulation factors with reduced relative dose intensity in women with breast cancer

Association of pre-chemotherapy peripheral blood pro-inflammatory and coagulation factors with reduced relative dose intensity in women with breast cancer

Abstract Background Chemotherapy decreases the risk of relapse and mortality in early-stage breast cancer (BC), but it comes with the risk of toxicity. Chemotherapy efficacy depends on relative dose intensity (RDI), and an RDI < 85% is associated with worse overall survival. The pro-inflammatory...

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Bibliographic Details
Main Authors: Yuan Yuan, Nilesh Vora, Can-Lan Sun, Daneng Li, Enrique Soto-Perez-de-Celis, Joanne Mortimer, The-hang Luu, George Somlo, James Waisman, David Smith, Joseph Chao, Vani Katheria, Timothy Synold, Vivi Tran, Shu Mi, Abrahm Levi, Anait Arsenyan, Jennifer Choi, Laura Zavala, Susan Yost, Arti Hurria
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Breast Cancer Research
Subjects:
Breast Cancer
Older adults
Aging
Biomarkers
Activities of Daily Living
Blood coagulation factors
Online Access:http://link.springer.com/article/10.1186/s13058-017-0895-5

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http://link.springer.com/article/10.1186/s13058-017-0895-5

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