Enhancement of in vivo hypoglycemic effect of gliclazide by developing self-microemulsifying pellet dosage form

Enhancement of in vivo hypoglycemic effect of gliclazide by developing self-microemulsifying pellet dosage form

Abstract Background The present research was aimed to develop a self-microemulsifying drug delivery system (SMEDDS) pellet to increase the dissolution rate and in vivo hypoglycemic effect of gliclazide. Gliclazide belongs to BCS class 2 and it exhibits dissolution rate-limited absorption. Thus, diss...

Full description

Bibliographic Details
Main Authors: Hetal Patel, Niharika Pandey, Bhoomi Patel, Ketan Ranch, Kunjan Bodiwala, Bhavin Vyas
Format: Article
Language:English
Published: SpringerOpen 2020-05-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
SMEDDS
Hypoglycemic
Tween
Pellets
Extrusion
Dissolution
Online Access:http://link.springer.com/article/10.1186/s43094-020-00034-0

Internet

http://link.springer.com/article/10.1186/s43094-020-00034-0

Similar Items