Neuroprotective mechanism of TMP269, a selective class IIA histone deacetylase inhibitor, after cerebral ischemia/reperfusion injury

Neuroprotective mechanism of TMP269, a selective class IIA histone deacetylase inhibitor, after cerebral ischemia/reperfusion injury

TMP269 is a selective class IIA histone deacetylase inhibitor that has a protective effect on the central nervous system, whose specific mechanism of action is unclear. We aimed to reveal the optimal concentration of TMP269 for protecting against cerebral ischemia/reperfusion injury and its neuropro...

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Bibliographic Details
Main Authors: Lu Su, Dan Liang, Shen-Yi Kuang, Qiang Dong, Xiang Han, Zheng Wang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Neural Regeneration Research
Subjects:
blood-brain barrier; drug treatment; endothelial cell permeability; histone deacetylase inhibitor; neuroprotection; stroke; tissue kallikrein; TMP269
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=2;spage=277;epage=284;aulast=Su

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=2;spage=277;epage=284;aulast=Su

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