Effect of Ca2+ on the promiscuous target-protein binding of calmodulin.

Calmodulin (CaM) is a calcium sensing protein that regulates the function of a large number of proteins, thus playing a crucial part in many cell signaling pathways. CaM has the ability to bind more than 300 different target peptides in a Ca2+-dependent manner, mainly through the exposure of hydroph...

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Bibliographic Details
Main Authors: Annie M Westerlund, Lucie Delemotte
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-04-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5898786?pdf=render