Composition and function of T cell subpopulations are slow to change despite effective antiretroviral treatment of HIV disease.

The ability to reconstitute a normal immune system with antiretroviral therapy in the setting of HIV infection remains uncertain. This study aimed to characterize quantitative and qualitative aspects of various T cell subpopulations that do not improve despite effective ART. CD4∶CD8 ratio was evalua...

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Bibliographic Details
Main Authors: Brinda Emu, Walter J Moretto, Rebecca Hoh, Melissa Krone, Jeffrey N Martin, Douglas F Nixon, Steven G Deeks, Joseph M McCune
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3897457?pdf=render