Identification of Discriminating Metabolic Pathways and Metabolites in Human PBMCs Stimulated by Various Pathogenic Agents

Identification of Discriminating Metabolic Pathways and Metabolites in Human PBMCs Stimulated by Various Pathogenic Agents

Immunity and cellular metabolism are tightly interconnected but it is not clear whether different pathogens elicit specific metabolic responses. To address this issue, we studied differential metabolic regulation in peripheral blood mononuclear cells (PBMCs) of healthy volunteers challenged by Candi...

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Bibliographic Details
Main Authors: Xiang Zhang, Adil Mardinoglu, Leo A. B. Joosten, Jan A. Kuivenhoven, Yang Li, Mihai G. Netea, Albert K. Groen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Physiology
Subjects:
innate immunity
metabolism
peripheral blood mononuclear cell
Candida albicans
lipopolysaccharides
Mycobacterium tuberculosis
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2018.00139/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2018.00139/full

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