In vitro effects of levosimendan on muscle of malignant hyperthermia susceptible and non-susceptible swine

In vitro effects of levosimendan on muscle of malignant hyperthermia susceptible and non-susceptible swine

Abstract Background The calcium sensitizer levosimendan is increasingly used to improve hemodynamics in patients with acutely decompensated heart failure. By binding to cardiac troponin C the conformation of the calcium-troponin C complex is stabilized, which leads to acceleration of actin-myosin cr...

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Bibliographic Details
Main Authors: Frank Schuster, Stephan Johannsen, Susanne Isbary, Ismail Türkmeneli, Norbert Roewer
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Anesthesiology
Subjects:
Malignant hyperthermia
Levosimendan
Muscle
Pigs
In vitro contracture test
Online Access:http://link.springer.com/article/10.1186/s12871-018-0644-z

Internet

http://link.springer.com/article/10.1186/s12871-018-0644-z

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