The Cholesterol-Lowering Effect of Capsella Bursa-Pastoris Is Mediated via SREBP2 and HNF-1α-Regulated PCSK9 Inhibition in Obese Mice and HepG2 Cells

The objective of the present study was to investigate the mechanism by which capsella bursa-pastoris ethanol extract (CBE), containing 17.5 milligrams of icaritin per kilogram of the extract, and icaritin, mediate hypocholesterolemic activity via the low-density lipoprotein receptor (LDLR) and pro-p...

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Bibliographic Details
Main Authors: Jin-Taek Hwang, Eunji Choi, Hyo-Kyoung Choi, Jae-Ho Park, Min-Yu Chung
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Foods
Subjects:
Online Access:https://www.mdpi.com/2304-8158/10/2/408