The Anti-tumour Agent, Cisplatin, and its Clinically Ineffective Isomer, Transplatin, Produce Unique Gene Expression Profiles in Human Cells

Cisplatin is a DNA-damaging anti-cancer agent that is widely used to treat a range of tumour types. Despite its clinical success, cisplatin treatment is still associated with a number of dose-limiting toxic side effects. The purpose of this study was to clarify the molecular events that are importan...

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Bibliographic Details
Main Authors: Anne M. Galea, Vincent Murray
Format: Article
Language:English
Published: SAGE Publishing 2008-01-01
Series:Cancer Informatics
Online Access:https://doi.org/10.4137/CIN.S802