BicaudalD actively regulates microtubule motor activity in lipid droplet transport.

A great deal of sub-cellular organelle positioning, and essentially all minus-ended organelle transport, depends on cytoplasmic dynein, but how dynein's function is regulated is not well understood. BicD is established to play a critical role in mediating dynein function-loss of BicD results in...

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Bibliographic Details
Main Authors: Kristoffer S Larsen, Jing Xu, Silvia Cermelli, Zhanyong Shu, Steven P Gross
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2582182?pdf=render