Aquaporin-4 autoantibodies in Neuromyelitis Optica: AQP4 isoform-dependent sensitivity and specificity.

Aquaporin-4 autoantibodies in Neuromyelitis Optica: AQP4 isoform-dependent sensitivity and specificity.

Neuromyelitis Optica (NMO) is an autoimmune demyelinating disease, characterized by the presence of autoantibody (NMO-IgG) to Aquaporin-4 (AQP4). NMO-IgG identification supports NMO diagnosis and several diagnostic tests have been developed, but their sensitivity is too variable, and some assay show...

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Bibliographic Details
Main Authors: Francesco Pisani, Angelo Sparaneo, Carla Tortorella, Maddalena Ruggieri, Maria Trojano, Maria Grazia Mola, Grazia Paola Nicchia, Antonio Frigeri, Maria Svelto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3829826?pdf=render

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http://europepmc.org/articles/PMC3829826?pdf=render

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