ALDH isozymes downregulation affects cell growth, cell motility and gene expression in lung cancer cells

<p>Abstract</p> <p>Background</p> <p>Aldehyde dehydrogenase isozymes ALDH1A1 and ALDH3A1 are highly expressed in non small cell lung cancer. Neither the mechanisms nor the biologic significance for such over expression have been studied.</p> <p>Methods</p...

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Bibliographic Details
Main Authors: Lopez M Cecilia, Amaya Maria, Chang Lung-Ji, Baker Henry V, Moreb Jan S, Ostmark Blanca, Chou Wayne
Format: Article
Language:English
Published: BMC 2008-11-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/7/1/87