Loss of interleukin-12 modifies the pro-inflammatory response but does not prevent duct obstruction in experimental biliary atresia

<p>Abstract</p> <p>Background</p> <p>Livers of infants with biliary atresia and of neonatal mice infected with rotavirus (RRV) have increased expression of interferon-gamma (IFNγ) and interleukin (IL)-12. While the expression of IFNγ regulates the obstruction of extrahe...

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Bibliographic Details
Main Authors: Bezerra Jorge A, Sabla Gregg, Shivakumar Pranavkumar, Mohanty Sujit
Format: Article
Language:English
Published: BMC 2006-04-01
Series:BMC Gastroenterology
Online Access:http://www.biomedcentral.com/1471-230X/6/14