Impact of Bone Marrow miR-21 Expression on Acute Myeloid Leukemia T Lymphocyte Fragility and Dysfunction

Impact of Bone Marrow miR-21 Expression on Acute Myeloid Leukemia T Lymphocyte Fragility and Dysfunction

Background: Acute myeloid leukemia (AML) is a hematopoietic malignancy in which antitumor immunity is impaired. The therapeutic management of AML requires understanding the mechanisms involved in the fragility and immune dysfunction of AML T lymphocytes. Methods: In this study, T lymphocytes from he...

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Bibliographic Details
Main Authors: Douâa Moussa Agha, Redouane Rouas, Mehdi Najar, Fatima Bouhtit, Hussein Fayyad-Kazan, Laurence Lagneaux, Dominique Bron, Nathalie Meuleman, Philippe Lewalle, Makram Merimi
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cells
Subjects:
AML
T lymphocytes
extracellular vesicles
miR21
apoptosis
immunosuppression
Online Access:https://www.mdpi.com/2073-4409/9/9/2053

Internet

https://www.mdpi.com/2073-4409/9/9/2053

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