Early Treatment Critical: Bexarotene Reduces Amyloid-Beta Burden In Silico.

Amyloid-beta peptides have long been implicated in the pathology of Alzheimer's disease. Bexarotene, a drug approved by the U.S. Food and Drug Administration for treating a class of non-Hodgkin's lymphoma, has been reported to facilitate the removal of amyloid-beta. We have developed a mat...

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Bibliographic Details
Main Authors: Joseph Rosenthal, Georges Belfort, David Isaacson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4830620?pdf=render