A Quantitative Serum Proteomic Analysis Helps to Explore the Comprehensive Mechanism and Identify Serum Biomarkers of Shengmai Injection’s Effect on Isoproterenol-Induced Myocardial Ischemia in Rats

A Quantitative Serum Proteomic Analysis Helps to Explore the Comprehensive Mechanism and Identify Serum Biomarkers of Shengmai Injection’s Effect on Isoproterenol-Induced Myocardial Ischemia in Rats

Shengmai injection (SMI), a traditional Chinese medicine formula with the nature of multicomponent and multi-target, has been widely used in clinic for treating cardiovascular diseases in China; however, its comprehensive mechanism of action remains unclear. In this study, a TMT-based quantitative s...

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Bibliographic Details
Main Authors: Xiaoping Zhang, Jie Zhang, Xiangyu Ji, Zhenzhen Wei, Baoyue Ding, Guoqiang Liu, Xiaoqing Lv, Yongxia Zheng, Shuyu Zhan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
Shengmai injection
serum proteomics
TMT
myocardial ischemia
serum biomarkers
glyceraldehyde-3-phosphate dehydrogenase
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.666429/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.666429/full

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