NADPH Oxidase and the Degeneration of Dopaminergic Neurons in Parkinsonian Mice

Several lines of investigation have implicated oxidative stress in Parkinson’s disease (PD) pathogenesis, but the mechanisms involved are still unclear. In this study, we characterized the involvement of NADPH oxidase (Nox), a multisubunit enzyme that catalyzes the reduction of oxygen, in the 6-hydr...

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Bibliographic Details
Main Authors: Marina S. Hernandes, Cecília C. Café-Mendes, Luiz R. G. Britto
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2013/157857