A Bacillus-based Coxsackie virus A16 mucosal vaccine induces strong neutralizing antibody responses

The purpose of this study was to construct a Coxsackie virus A16 (CA16) mucosal vaccine and evaluate its ability to induce immune response. VP1 gene of CA16 was inserted into the genome of Bacillus subtilis via recombination and displayed on the surface of the spores. This Bacillus-based vaccine was...

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Bibliographic Details
Main Authors: Yin-Guang Cao, Yu Hao, Lexin Wang
Format: Article
Language:English
Published: Termedia Publishing House 2019-04-01
Series:Central European Journal of Immunology
Subjects:
vp1
Online Access:https://www.termedia.pl/A-Bacillus-based-Coxsackie-virus-A16-mucosal-vaccine-induces-strong-neutralizing-antibody-responses,10,36198,1,1.html