Transcriptome sequencing of the human pathogen Corynebacterium diphtheriae NCTC 13129 provides detailed insights into its transcriptional landscape and into DtxR-mediated transcriptional regulation

Transcriptome sequencing of the human pathogen Corynebacterium diphtheriae NCTC 13129 provides detailed insights into its transcriptional landscape and into DtxR-mediated transcriptional regulation

Abstract Background The human pathogen Corynebacterium diphtheriae is the causative agent of diphtheria. In the 1990s a large diphtheria outbreak in Eastern Europe was caused by the strain C. diphtheriae NCTC 13129. Although the genome was sequenced more than a decade ago, not much is known about it...

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Bibliographic Details
Main Authors: Manuel Wittchen, Tobias Busche, Andrew H. Gaspar, Ju Huck Lee, Hung Ton-That, Jörn Kalinowski, Andreas Tauch
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Genomics
Subjects:
Corynebacterium diphtheriae
Transcriptome sequencing
RNA-Seq
Transcription start site
Promoter
DtxR
Online Access:http://link.springer.com/article/10.1186/s12864-018-4481-8

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http://link.springer.com/article/10.1186/s12864-018-4481-8

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